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Elleste duet

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Elleste Duet is a hormonal medication for menopausal women. It contains the active substance estradiol, which is a natural form of the female sex hormone estrogen. Elleste Duet tablets can be used as a supplement to compensate for the drop in hormone levels in the body and help reduce the bothersome symptoms of menopause. This type of treatment is known as hormone replacement therapy (HRT), or simply hormone therapy (HT). Elleste Duet is a prescription-only medicine.

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Elleste Duet are used as hormone replacement therapy (HRT), used to manage symptoms of the menopause. It contains estradiol, which is chemically similar to the female hormone oestrogen. During the menopause, the production of oestrogen in a woman’s ovaries gradually stops. This deficiency can lead to a number of symptoms, including hot flushes, depression, sleep problems, dryness and osteoporosis. If these symptoms are sufficiently severe, you may be prescribed Elleste Solo in order to supplement the body’s oestrogen levels. Elleste Duet is available in 1mg and 2mg strengths.

What is Elleste?

Elleste Duet is a hormone replacement therapy (HRT) that is used for women in menopause or postmenopause. Elleste Duet tablets contain estradiol (an estrogen hormone). This active ingredient supplements hormonal deficiencies, alleviating the symptoms of menopause. This HRT treatment medication is a prescription-only medicine.

How does it work?

In blood plasma, most estradiol is bound to sex hormone-binding globulin (SHBG), and also to albumin. Only a fraction of 2.21% (+/- 0.04%) is free and biologically active, the remaining percentage remains constant throughout the menstrual cycle. Deactivation includes conversion to less active estrogen, such as estrone and estriol. Estradiol is the main urinary metabolite. Estradiol is conjugated in the liver by the formation of sulfate and glucuronide and, as such, excreted through the kidneys. Some water-soluble conjugates are excreted through the bile duct and are partially reabsorbed after hydrolysis of the intestinal tract. This enterohepatic circulation contributes to the maintenance of estradiol levels.

What are the benefits of taking it?

Elleste is one of the hormone replacement therapies (HRT). This HRT contains estradiol hemihydrate, which is an estrogen (a female hormone). Elleste Solo is for postmenopausal women experiencing menopausal symptoms and, when other medications are not appropriate, they are used to stop the development of osteoporosis (bone fragility).

How do I use it and its dosage?

Elleste is supplied as a tablet (dose: 1 mg or 2 mg) or as a skin patch (transdermal) (dose: 40 μg or 80 μg). The dose you will be given will be adequate for your symptoms. Estradiol enters the blood through your digestive system when you swallow a tablet or through your skin when you apply a patch.

Tablets

If you have regular periods, the tablets start on the first day of bleeding; if you have irregular periods, the tablets can start at any time. Swallow one tablet whole every day, preferably at the same time, with a glass of water. Take the tablets in sequence as directed on the foil strip, and when you finish the strip, start another strip the next day.

Patches

If you have regular periods, the patches start within 5 days after the first day of bleeding; If you have irregular periods, the patches can start at any time. The patches should be attached to clean, dry, undamaged, normal skin below the waist (for example, the buttocks or lower back) and never near the breasts. Remove the patch from the bag, then peel off the smaller back cover on the adhesive side and adhere to the chosen skin area.

As you flatten the patch with one hand, remove the remaining back cover with the other hand and press firmly. Change the patch every 3 or 4 days (on the same days every week), using two patches per week. Fold the old patch, place it in the empty package, and dispose of it responsibly. The patch will not come off  when bathing and showering if it is firmly attached.

Side effects & precautions

It is essential that you inform your doctor about any Elleste side effects that you may experience. Some of these may require urgent medical attention. These include any signs of a blood clot; heart attack; stroke; an allergic reaction; memory loss if used at an age above 65 years; endometrial hyperplasia; or breast, cervical, or ovarian cancer.

Very common (1 in 10 people or more):

Tenderness in the breasts, intermittent bleeding, or headache.

Common (1 in 10 people or less):

Mild irritation at the site of application, stomach cramps, growth of fibroids in the uterus, weight fluctuations, swelling in the legs, mood changes, or changes in sexual desire.

Uncommon (1 in 100 people or less):

Indigestion, flatulence, gallstones, dizziness, migraines, vaginal yeast infections, increased blood pressure, or leg cramps.

Rare (1 in 1,000 people or less):

Hair loss, itching, or skin rash.

Precautions and Warnings

Women who have or have ever had the following should not use this product: breast cancer; any type of cancer that is sensitive to estrogen; unexplained vaginal bleeding; lactose intolerance; excessive thickening of the endometrium; a blood clot in a vein; liver disease; porphyria; any disorder that affects blood clotting; a heart attack or stroke; angina.

It may also not be suitable for women with a history of the following, or may only be prescribed with special caution in these cases: fibroids in the uterus; the growth of the lining of the uterus outside the womb, or an overgrowth of the endometrial lining; any condition that increases the risk of estrogen-sensitive blood clots or cancers; high triglyceride levels; otosclerosis; asthma; high blood pressure; liver disease; diabetes; gallstones; systemic lupus erythematosus; migraines; epilepsy; or fluid retention due to heart or kidney problems.

types

Duet 1mg – 168 Tablets (6 Months), Duet 1mg – 84 Tablets (3 months), Duet 2mg – 168 Tablets (6 Months), Duet 2mg – 84 Tablets (3 months), Duet Conti – 168 Tablets (6 Months)

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